Friday, May 31, 2013

Gene Therapy May Protect Against Flu

That's mostly a risk if you're using a virus vector which integrates the DNA into an existing chromosome (which this one doesn't, I believe), AND you can't control the site of insertion. That is, unless the specific gene (in this case, the antibody gene) itself can cause a persistent change in the function of the cell - maybe causing the body to produce a compound which itself promotes cell growth or the like. (That's well outside my area of expertise.)

The great thing about inserting into an existing chromosome (which this does not do) is that then cell replication *does* propagate the gene. The downside is the risk of incorrect insertion which can lead to cancer, among other things.

Source: http://rss.slashdot.org/~r/Slashdot/slashdotScience/~3/z937ACm-5tA/story01.htm

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